Hiv-1 Reverse Transcriptase, Molecular
by Juan Gaertner
Title
Hiv-1 Reverse Transcriptase, Molecular
Artist
Juan Gaertner
Medium
Photograph - Photograph
Description
HIV-1 reverse transcriptase (RT) complexed with two different inhibitors. Left RT with a 30 nucleoside inhibitor (orange), right RT with a non nucleoside inhibitor (yellow). The human immunodeficiency virus single-stranded RNA genome is converted into double-stranded DNA by the viral reverse transcriptase and then the DNA is integrated in the DNA of an infected human cell. The reverse transcriptase is one of the main targets to disrupt the virus multiplication through an inhibitor. There are nucleoside and nucleotide inhibitors and non nucleoside analogue inhibitors.
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October 14th, 2018
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