Cytokine Storm
by Eye of Science
Title
Cytokine Storm
Artist
Eye of Science
Medium
Photograph - Photograph
Description
This image is a composite of different SEM images of cells from the immune system to illustrate a cytokine storm. The small cells are different types of leukocytes; the large ones are macrophages. During a normal immune system reaction, the immune cells produce cytokines that attract other cells, which also release cytokines. In a cytokine storm (also called hypercytokinemia), the immune system releases very high concentrations of cytokines. This activates leukocytes so intensively that the immune reaction does not automatically calm down. This may impair the function of the tissue and lead to organ failure. A cytokine storm can arise especially with CAR-T-cell therapy, as this therapy aims at T-cell activation. Cytokine storms can also occur with virally or bacterially induced diseases. That was observed in sepsis (blood poisoning), EBOLA fever, COVID-19, avian flu, smallpox and rabbit fever.
Scanning electron micrograph; magnification 1500x (at 15 cm image width).
Uploaded
October 19th, 2020
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