Car T-cell Immunotherapy
by Juan Gaertner
Title
Car T-cell Immunotherapy
Artist
Juan Gaertner
Medium
Photograph - Photograph
Description
CAR T-cell (Chimeric antigen receptor) immunotherapy. Engineered receptors (light blue) on the surface of a T-lymphocyte bind specifically to CD19-antigen molecules (magenta) on a leukemia cell. This activates a signal cascade in the T-cell leading to the segregation of vesicles that contain perforin and granzyme (yellow) molecules. The perforins build channels for the granzymes which enter the leukemia cell and activate finally the apoptosis (cell death) of the cancer cell. 3D computer illustration.
Uploaded
October 14th, 2018
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