Female Human Chromosomes, Normal, Sky
by Science Source
Title
Female Human Chromosomes, Normal, Sky
Artist
Science Source
Medium
Photograph - Photograph
Description
Normal human chromosomes visualized by spectral karyotyping (SKY). Spectral karyotyping is a molecular cytogenetic technique used to simultaneously visualize all the pairs of chromosomes in an organism in different colors. Fluorescently labeled probes for each chromosome are made by labeling chromosome-specific DNA with different fluorophores. Because there are a limited number of spectrally distinct fluorophores, a combinatorial labeling method is used to generate many different colors. Spectral differences generated by combinatorial labeling are captured and analyzed by using an interferometer attached to a fluorescence microscope. Image processing software then assigns a pseudo color to each spectrally different combination, allowing the visualization of the individually colored chromosomes. This technique is used to identify structural chromosome aberrations in cancer cells and other disease conditions when Giemsa banding or other techniques are not accurate enough.
Uploaded
August 5th, 2015
Embed
Share
Comments
There are no comments for Female Human Chromosomes, Normal, Sky. Click here to post the first comment.