Erythropoiesis #1
by Anatomical Travelogue
Title
Erythropoiesis #1
Artist
Anatomical Travelogue
Medium
Photograph - Photograph
Description
Medical visualization taken from human scanned data showing erythropoiesis, or the production of a red blood cell. This process takes place within bone marrow, and is necessary as red blood cells are incapable of reproduction. Erythropoiesis follows 7 stages, including 3 phases of development. The first stage is a hemocytoblast stem cell which begins the stem cell development. The hemocytoblast becomes a myeloid progenitor stem cell (stage 2), and finally a unipotent stem cell (stage 3, pictured). The stem cell transforms into a committed cell or proerythroblast (stage 4, pictured), and then moves on to phase 1 of the developmental pathway as a basophilic normoblast or early erythroblast (stage 5, pictured). Erythropoietin (a hormone that is produced by the kidneys) binds to the cell to make the late erythroblast or polychromatophilic erythroblast (stage 6, pictured), which begins phase 2 of the developmental pathway. As its name suggests, the polychomatophilic erythroblast has multiple chromosomes within it. The late erythroblast develops into a orthochromatophilic normoblast (stage 7, pictured) and ejects it’s nucleus. The reticulocyte is formed at phase 3 as part of the last stage of erythropoiesis. A reticulocyte will become an erythrocyte (red blood cell) within 48 hours and will move from the bone marrow to the bloodstream.
Uploaded
September 15th, 2018
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