Breast Cancer Cells With Car Cells, Sem
by Meckes/ottawa
Title
Breast Cancer Cells With Car Cells, Sem
Artist
Meckes/ottawa
Medium
Photograph - Photograph
Description
Color enhanced scanning electron microscope image of breast cancer cells (adenocarcinoma) of the line MDA-MB-231. On the cancer cell sits a chimera antigen receptor cell (red). CAR cells are used for immunotherapy against cancer. In this form of immunotherapy, T cells are obtained from the patient's blood and are modified by viral vectors to additionally express a chimeric antigen receptor (CAR) recognizing a specific tumor antigen. After the multiplication of these CAR-expressing T cells in vitro, they are transfused back into the patient and can directly detect the cancer cells carrying the antigen. If the CAR-T cell binds to a tumor cell, the CAR-T cell is activated and appropriate immune defense is initiated. Not all CAR cells can successfully destroy the cancer cells. This cell has been converted into apoptosis (cell suicide), which can be seen in the formation of blisters on the cell surface. Magnification is 2335x at 10 cm wide.
Uploaded
May 19th, 2021
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